TIPS FOR TAKING ENTRESTO

ENTRESTO is a film-coated tablet that comes in the following doses: 24/26 mg, 49/51 mg, and 97/103 mg. It comes in these doses because it contains two medicines, which enable it to work two ways. Remember, you should only take the exact dose as prescribed by your doctor.

ENTRESTO is a film-coated tablet that comes in the following doses: 24/26 mg, 49/51 mg, and 97/103 mg. It comes in these doses because it contains two medicines, which enable it to work two ways. Remember, you should only take the exact dose as prescribed by your doctor.

Before starting ENTRESTO

ENTRESTO is usually taken with other Heart Failure medicines, in place of an ACE inhibitor or other ARB. If you have been prescribed ENTRESTO and are currently taking an ACE inhibitor*:

*Such as enalapril or lisinopril.

Stop taking your ACE inhibitor*. Wait for 36 hours. Go Start taking ENTRESTO as prescribed.

*Such as enalapril or lisinopril.

entresto is a twice-daily medicine

Taking it at the same time each day—for example, when you first wake up and again before you go to bed—may make you less likely to miss a dose. ENTRESTO can also be taken with or without food.

How to take entresto

ENTRESTO is a tablet that comes in the following doses:

 ENTRESTO 24/26mg pill
ENTRESTO 49/51mg pill
ENTRESTO 97/103mg pill

You should take your dose of ENTRESTO exactly as prescribed by the doctor. Keep in mind: You should not take an ACE inhibitor and ENTRESTO together.

When taking ENTRESTO, it is
important to follow the treatment
plan prescribed by your doctor

If you stop taking ENTRESTO, the medicine will stop working for you. But since ENTRESTO can be taken with or without food, it can easily fit into your daily routine. You may even be able to take ENTRESTO along with other medicines—just check with your doctor or pharmacist first.

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You’re not alone. Now you can connect with someone like you.

Voices with Heart provides an opportunity for you to speak directly with someone who
is currently taking ENTRESTO in a private, one-on-one telephone conversation.

Once you sign up, we will connect you with one of our ENTRESTO patient mentors, who can share
their experiences living with chronic Heart Failure at a date and time that works for you.

Please note: Patient mentors cannot give you medical advice or recommend treatments—those topics should be discussed with your doctor.

Are you on ENTRESTO?

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But were recently diagnosed or hospitalized with Heart Failure?

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See how people who take ENTRESTO are living with Heart Failure

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IMPORTANT SAFETY INFORMATION

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What is the most important information I should know about ENTRESTO?

ENTRESTO can harm or cause death to your unborn baby. Talk to your doctor about other ways to treat heart failure if you plan to become pregnant. If you get pregnant during treatment with ENTRESTO, tell your doctor right away.

Do not take ENTRESTO if you:

  • are allergic to any of the ingredients in ENTRESTO
  • have had an allergic reaction including swelling of your face, lips, tongue, throat (angioedema) or trouble breathing while taking a type of medicine called an angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB)
  • take an ACE inhibitor medicine. Do not take ENTRESTO for at least 36 hours before or after you take an ACE inhibitor medicine. Talk with your doctor or pharmacist before taking ENTRESTO if you are not sure if you take an ACE inhibitor medicine
  • have diabetes and take a medicine that contains aliskiren

INDICATION

What is ENTRESTO?

ENTRESTO is a prescription medicine used to treat adults with long-lasting (chronic) heart failure to help reduce the risk of death and hospitalization. ENTRESTO works better when the heart cannot pump a normal amount of blood to the body.

Before taking ENTRESTO tell your doctor about all of your medical conditions, including if you:

  • have a history of hereditary angioedema
  • have kidney or liver problems
  • are pregnant or plan to become pregnant; are breastfeeding or plan to breastfeed. You should either take ENTRESTO or breastfeed. You should not do both

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take potassium supplements or a salt substitute; nonsteroidal anti-inflammatory drugs (NSAIDs); lithium; or other medicines for high blood pressure or heart problems such as an ACE inhibitor, ARB, or aliskiren.

What are the possible side effects of ENTRESTO?

ENTRESTO may cause serious side effects including:

  • Swelling of your face, lips, tongue and throat (angioedema) that may cause trouble breathing and death. Get emergency medical help right away if you have symptoms of angioedema or trouble breathing. Do not take ENTRESTO again if you have had angioedema while taking ENTRESTO
  • People who are Black or who have had angioedema and take ENTRESTO may have a higher risk of having angioedema
  • low blood pressure (hypotension), which may be more common if you take water pills. Call your doctor if you become dizzy or lightheaded, or you develop extreme fatigue
  • kidney problems
  • increased amount of potassium in your blood (hyperkalemia)

The most common side effects were low blood pressure, high potassium, cough, dizziness, and kidney problems.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATION

What is ENTRESTO?

ENTRESTO is a prescription medicine used to treat adults with long-lasting (chronic) heart failure to help reduce the risk of death and hospitalization. ENTRESTO works better when the heart cannot pump a normal amount of blood to the body.

This information is not comprehensive. Please see full Prescribing Information, including Boxed WARNING, and Patient Prescribing Information.