ABOUT ENTRESTO KEEPING UP WITH TREATMENT

With ENTRESTO, more tomorrows may be possible

When you have HF, keeping up with your prescribed treatment plan is the best way to help your heart stay healthy. Remember, ENTRESTO may help reduce the risk of death and hospitalization in people with HF, but it must be taken every day as prescribed. If you stop taking ENTRESTO, the medicine will stop working for you.

It's also important for people with HF to be open and honest with their doctor. Talking about how you feel puts you more in control of your condition and can make it easier for your doctor to treat you. For example, have you been having trouble sleeping? That might not seem like something your doctor needs to know, but it is. In fact, if you're having trouble doing any of the things you used to be able to do, let your doctor know.

To help steer your next conversation, you can create a personalized doctor discussion guide below. Once finished, either print or e-mail the guide to yourself and bring it with you to your next appointment.

Talking to your doctor

When discussing HF with your doctor, try to structure the conversation by focusing on the following 3 areas:

1. REPORT YOUR SYMPTOMS

When you have HF, it's important to keep a close watch on your symptoms. The following are symptoms commonly associated with HF. Click any that you have experienced since your last appointment.

New

Ongoing

2. SHARE YOUR PROGRESS

In addition to keeping up with treatment, making healthy lifestyle changes is also important for people with HF.

3. ASK QUESTIONS

You may have a lot of questions that you'd like to ask the doctor, but when you get to the appointment, you may feel overwhelmed and have a hard time remembering them all. Below are some common HF-related questions. Click any that you would like to discuss with the doctor.

Of course, you may have other questions that are not on this list. If there's anything else you'd like to ask your doctor, type it here:

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ENTRESTO?

ENTRESTO can harm or cause death to your unborn baby. Talk to your doctor about other ways to treat heart failure if you plan to become pregnant. If you get pregnant while taking ENTRESTO, tell your doctor right away.

INDICATION

What is ENTRESTO?

ENTRESTO is a prescription medicine used to reduce the risk of death and hospitalization in people with certain types of long-lasting (chronic) heart failure. ENTRESTO is usually used with other heart failure therapies, in place of an ACE inhibitor or other ARB therapy.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about ENTRESTO?

ENTRESTO can harm or cause death to your unborn baby. Talk to your doctor about other ways to treat heart failure if you plan to become pregnant. If you get pregnant while taking ENTRESTO, tell your doctor right away.

Who should not take ENTRESTO?

Do not take ENTRESTO if you:

  • are allergic to sacubitril or valsartan or any of the ingredients in ENTRESTO
  • have had an allergic reaction including swelling of your face, lips, tongue, throat (angioedema) or trouble breathing while taking a type of medicine called an angiotensin-converting enzyme (ACE) inhibitor or angiotensin II receptor blocker (ARB)
  • take an ACE inhibitor medicine. Do not take ENTRESTO for at least 36 hours before or after you take an ACE inhibitor medicine. Talk with your doctor or pharmacist before taking ENTRESTO if you are not sure if you take an ACE inhibitor medicine
  • have diabetes and take a medicine that contains aliskiren

What should I tell my doctor before taking ENTRESTO?

Before you take ENTRESTO, tell your doctor about all of your medical conditions, including if you have kidney or liver problems; are pregnant or plan to become pregnant; are breastfeeding or plan to breastfeed. You should either take ENTRESTO or breastfeed. You should not do both.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Especially tell your doctor if you take potassium supplements or a salt substitute; nonsteroidal anti-inflammatory drugs (NSAIDs); lithium; or other medicines for high blood pressure or heart problems such as an ACE inhibitor, ARB, or aliskiren.

What are the possible side effects of ENTRESTO?

ENTRESTO may cause serious side effects including:

  • angioedema that may cause trouble breathing and death. Get emergency medical help right away if you have symptoms of angioedema or trouble breathing. Do not take ENTRESTO again if you have had angioedema while taking ENTRESTO. People who are Black or who have had angioedema and take ENTRESTO may have a higher risk of having angioedema
  • low blood pressure (hypotension). Call your doctor if you become dizzy or lightheaded, or you develop extreme fatigue
  • kidney problems
  • increased amount of potassium in your blood

The most common side effects were low blood pressure, high potassium, cough, dizziness, and kidney problems.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

INDICATION

What is ENTRESTO?

ENTRESTO is a prescription medicine used to reduce the risk of death and hospitalization in people with certain types of long-lasting (chronic) heart failure. ENTRESTO is usually used with other heart failure therapies, in place of an ACE inhibitor or other ARB therapy.

This information is not comprehensive. Please see full Prescribing Information, including Boxed WARNING, and Patient Prescribing Information.

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